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TCS PIM-1 1 (SC 204330) is a potent and selective inhibitor of ATP-competitive Pim-1 kianse with IC50 of 50 nM, shows good selectivity over Pim-2 and MEK1/MEK2 with IC50 > 20000 nM.
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An ATP competitive Pim 1 kinase inhibitor IC50 50 nM that displays selectivity over the related kinases Pim 2 and MEK1 2 IC50s 20 µM
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Image Search Results
Journal: iScience
Article Title: Pim-1 kinase protects the liver from ischemia reperfusion injury by regulating dynamics-related protein 1
doi: 10.1016/j.isci.2024.110280
Figure Lengend Snippet:
Article Snippet: The
Techniques: Recombinant, TUNEL Assay, AST Assay, Bicinchoninic Acid Protein Assay, Software